Inter‐viral conflicts that exploit host CRISPR immune systems of S ulfolobus
نویسندگان
چکیده
منابع مشابه
CRISPR-Cas: the effective immune systems in the prokaryotes
Approximately all sequenced archaeal and half of eubacterial genomes have some sort of adaptive immune system, which enables them to target and cleave invading foreign genetic elements by an RNAi-like pathway. CRISPR–Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) systems consist of the CRISPR loci with multiple copies of a short repeat sequence separa...
متن کاملCRISPR-based adaptive immune systems.
CRISPR-Cas systems are recently discovered, RNA-based immune systems that control invasions of viruses and plasmids in archaea and bacteria. Prokaryotes with CRISPR-Cas immune systems capture short invader sequences within the CRISPR loci in their genomes, and small RNAs produced from the CRISPR loci (CRISPR (cr)RNAs) guide Cas proteins to recognize and degrade (or otherwise silence) the invadi...
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متن کاملCRISPR adaptive immune systems of Archaea
CRISPR adaptive immune systems were analyzed for all available completed genomes of archaea, which included representatives of each of the main archaeal phyla. Initially, all proteins encoded within, and proximal to, CRISPR-cas loci were clustered and analyzed using a profile-profile approach. Then cas genes were assigned to gene cassettes and to functional modules for adaptation and interferen...
متن کاملcrispr-cas: the effective immune systems in the prokaryotes
approximately all sequenced archaeal and half of eubacterial genomes have some sort of adaptive immune system, which enables them to target and cleave invading foreign genetic elements by an rnai-like pathway. crispr–cas (clustered regularly interspaced short palindromic repeats–crispr-associated proteins) systems consist of the crispr loci with multiple copies of a short repeat sequence separa...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2014
ISSN: 0950-382X,1365-2958
DOI: 10.1111/mmi.12503